Forschung
Publikationen

Publikationen AG Witte

  • Niehaus, M., Straube, H., Specht, A., Baccolini, C., Witte, C.-P., Herde, M. (2022): The nucleotide metabolome of germinating Arabidopsis thaliana seeds reveals a central role for thymidine phosphorylation in chloroplast developmentThe Plant Cell 34, 3790-3813.
    DOI: 10.1093/plcell/koac207
  • Voß, L., Heinemann K.J., Herde, M., Medina-Escobar, N., Witte, C.-P. (2022): Enzymes and cellular interplay required for flux of fixed nitrogen to ureides in bean nodules.Nature Communications 13, 5331
    DOI: 10.1038/s41467-022-33005-5
  • Heinemann, K. J., Yang, S.-Y., Straube H., Medina-Escobar N., Varbanova-Herde M., Herde M., Rhee S., Witte C.-P. (2021): Initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphataseNature Communications 12, 6846
    DOI: 10.1038/s41467-021-27152-4
  • Kim, S.-H., Witte, C.-P, Rhee, S. (2021): Structural basis for the substrate specificity and catalytic features of pseudouridine kinase from Arabidopsis thalianaNucleic Acids Research 49, 491–503.
    DOI: 10.1093/nar/gkaa1144
  • Rinne, J., Witte, C.-P. and Herde, M. (2021): Loss of MAR1 Function is a Marker for Co-Selection of CRISPR-Induced Mutations in PlantsFrontiers in Genome Editing, 09 August 2021
    DOI: 10.3389/fgeed.2021.723384
  • Straube, H., Witte, C.P., Herde, M. (2021): Analysis of Nucleosides and Nucleotides in Plants: An Update on Sample Preparation and LC–MS TechniquesCells 10, 689.
    DOI: 10.3390/cells10030689
  • Zhu et. al (u.a. Herde, M.) (2021): Calmodulin-like protein CML24 interacts with CAMTA2 and WRKY46 to regulate ALMT1-dependent Al resistance in Arabidopsis thalianaNew Phytologist 233, 2471–2487
    DOI: 10.1111/nph.17812
  • Chen, M., Witte, C.-P. (2020): A Kinase and a Glycosylase Catabolize Pseudouridine in the Peroxisome to Prevent Toxic Pseudouridine Monophosphate AccumulationThe Plant Cell 32, 722-739.
    DOI: 10.1105/tpc.19.00639
  • Durian G, Sedaghatmehr M, Matallana-Ramirez L P, Schilling S, Schaepe S, Guerra T, Herde M, Witte C-P, Müller-Röber B, Schulze W X, Balazadeh S, Romeis T (2020): Calcium-Dependent Protein Kinase CPK1 Controls Cell Death by In Vivo Phosphorylation of Senescence Master Regulator ORE1The Plant Cell 32, 1610-1625.
    DOI: 10.1105/tpc.19.00810
  • Niehaus, M., Straube, H., Künzler, P., Rugen, N., Hegermann, J., Giavalisco, P., Eubel, H., Witte, C.-P., Herde, M. (2020): Rapid affinity purification of tagged plant mitochondria (Mito-AP) for metabolome and proteome analysesPlant Physiology 182, 1194–1210.
    DOI: 10.1104/pp.19.00736
  • Safavi-Rizi, V., Herde, M. and Stöhr, C. (2020): RNA-Seq reveals novel genes and pathways associated with hypoxia duration and tolerance in tomato rootScientific Reports 10, 1-17.
  • Straube, H., Niehaus, M., Zwittian, S., Witte, C.-P., Herde, M. (2020): Enhanced nucleotide analysis enables the quantification of deoxynucleotides in plants and algae revealing connections between nucleoside and deoxynucleoside metabolismThe Plant Cell 33, 270–289.
    DOI: 10.1093/plcell/koaa028
  • Witte, C.-P. and Herde, M. (2020): Nucleotide metabolism in plantsPlant Physiology 182, 63–78.
    DOI: 10.1104/pp.19.00955
  • Baccolini, C., Witte, C.P. (2019): AMP and GMP Catabolism in Arabidopsis Converge on Xanthosine, which Is Degraded by a Nucleoside Hydrolase HeterocomplexThe Plant Cell 31, 734–751.
    DOI: 10.1105/tpc.18.00899
  • Chen, M. and Witte, C.-P. (2019): Functions and Dynamics of Methylation in Eukaryotic mRNAIn: Jurga S., Barciszewski J. (eds) The DNA, RNA, and Histone Methylomes. RNA Technologies. Springer, Cham, 333-351.
    DOI: 10.1007/978-3-030-14792-1_13
  • Kang, P.-A., Oh, J., Lee, H., Witte, C.-P., Rhee, S. (2019): Crystal structure and mutational analyses of ribokinase from Arabidopsis thalianaJournal of Structural Biology 206, 110-118.
    DOI: 10.1016/j.jsb.2019.02.007
  • Liu, B., Winkler, F., Herde, M., Witte, C.-P., Großhans, J. (2019): A link between deoxyribonucleotide metabolites and embryonic cell cycle controlCurrent Biology 29, 1187-1192.
    DOI: 10.1016/j.cub.2019.02.021
  • Chen, M., Urs, M.J., Sánchez-González, I., Olayioye, M.A., Herde, M., Witte C.-P. (2018): m6A RNA Degradation Products are Catabolized by an Evolutionarily Conserved N6-methyl-AMP Deaminase in Plant and Mammalian CellsThe Plant Cell 30, 1511–1522.
    DOI: 10.1105/tpc.18.00236
  • Kirchner, T.W., Niehaus, M., Rössig, K.L., Lauterbach, T., Herde, M., Küster, H. and Schenk , M.K. (2018): Molecular background of Pi deficiency-induced root hair growth in Brassica carinata – A fasciclin-like arabinogalactan protein is involvedFrontiers in Plant Science 9, 1372.
    DOI: 10.3389/fpls.2018.01372
  • Schroeder, R.Y., Zhu, A., Eubel, H., Dahncke, K., Witte, C.-P. (2018): The ribokinases of Arabidopsis thaliana and Saccharomyces cerevisiae are required for ribose recycling from nucleotide catabolism which in plants is not essential to survive prolonged dark stressNew Phytologist 217, 233-244.
    DOI: 10.1111/nph.14782
  • Kirchner, T.W., Niehaus, M., Debener, T., Schenk, M.K., Herde, M. (2017): Efficient generation of mutations mediated by CRISPR/Cas9 in the hairy root transformation system of Brassica carinataPLOS ONE 12, 0185429.
    DOI: 10.1371/journal.pone.0185429
  • Myrach, T., Zhu, A., Witte, C.-P. (2017): The assembly of the plant urease activation complex and the essential role of the urease accessory protein G (UreG) in delivery of nickel to ureaseThe Journal of Biological Chemistry 292, 14556-14565.
    DOI: 10.1074/jbc.M117.780403
  • Yang, Z.-B., He, C., Ma, Y., Herde, M., Ding, Z. (2017): Jasmonic acid enhances Al-induced root-growth inhibitionPlant Physiology 173, 1420–1433.
    DOI: 10.1104/pp.16.01756
  • Yilamujiang, A., Zhu, A., Ligabue-Braun, R., Bartram, S., Witte, C.-P., Hedrich, R., Hasabe, M., Schöner, C.R., Schöner, M.G., Kerth, G., Carlini, C.R. & Mithöfer, A. (2017): Coprophagous features in carnivorous Nepenthes plants: a task for ureasesScientific Reports 7, 11647.
    DOI: 10.1038/s41598-017-11999-z
  • Chen, M., Herde, M., Witte, C.P. (2016): Of the nine cytidine deaminase like genes in Arabidopsis thaliana eight are pseudogenes and only one is required to maintain pyrimidine homeostasis in vivoPlant Physiology 171, 799-809.
    DOI: 10.1104/pp.15.02031
  • Fleck, A.T., Schulze, S., Hinrichs, M., Specht, A., Waßmann, F., Schreiber, L., Schenk, M.K. (2015): Silicon Promotes Exodermal Casparian Band Formation in Si-Accumulating and Si-Excluding Species by Forming Phenol ComplexesPLoS ONE 10(9): e0138555.
    DOI: 10.1371/journal.pone.0138555
  • Klug, K., Hogekamp, C., Specht, A., Shwe Myint, S., Blöink, D., Küster, H., Horst, W.J. (2015): Spatial gene expression analysis in tomato hypocotyls suggests cysteine as key precursor of vascular sulfur accumulation implicated in Verticillium dahliae defensePhysiologia Plantarum 153, 253–268
  • Matschi, S., Hake, K., Herde, M., Hause, B. and Romeis, T. (2015): The Calcium-Dependent Protein Kinase CPK28 Regulates Development by Inducing Growth Phase-Specific, Spatially Restricted Alterations in Jasmonic Acid Levels Independent of Defense Responses in ArabidopsisThe Plant Cell 27, 591-606.
    DOI: 10.1105/tpc.15.00024​​
  • Hauck, O.K., Scharnberg, J., Medina Escobar, N., Wanner, G., Giavalisco, P., Witte, C.P. (2014): Uric acid accumulation in an Arabidopsis urate oxidase mutant impairs seedling establishment by blocking peroxisome maintenanceThe Plant Cell 26, 3090-3100.
    DOI: 10.1105/tpc.114.124008
  • Herde, M., Howe G.A. (2014): Host plant-specific remodeling of midgut physiology in the generalist insect herbivore Trichoplusia niInsect Biochemistry and Molecular Biology 50, 58-67.
    DOI: 10.1016/j.ibmb.2014.03.013
  • Romeis, T., Herde, M. (2014): From local to global: CDPKs in systemic defense signaling upon microbial and herbivore attackCurrent Opinion in Plant Biology 20, 1-10.
    DOI: 10.1016/j.pbi.2014.03.002
  • Bollig, K., Specht, A., Myint, S. S., Zahn, M., Horst, W. J. (2013): Sulphur supply impairs spread of Verticillium dahliae in tomatoEuropean Journal of Plant Pathology 135, 81-96
  • Chuang, W.-P., Herde, M., Ray, S., Castano-Duque, L., Howe, G.A., Luthe, D.S. (2013): Caterpillar attack triggers accumulation of the toxic maize protein RIP2New Phytologist 201, 928-939.
    DOI: 10.1111/nph.12581
  • Dahncke, K., Witte, C.P. (2013): Plant purine nucleoside catabolism employs a guanosine deaminase required for the generation of xanthosine in ArabidopsisThe Plant Cell 25, 4101-4109.
    DOI: 10.1105/tpc.113.117184
  • Dubiella, U., Seybold, H., Durian, G., Komander, E., Lassig, R., Witte, C.P., Schulze, W.X., Romeis, T. (2013): Calcium-dependent protein kinase/NADPH oxidase activation circuit is required for rapid defense signal propagationProceedings of the National Academy of Sciences of the United States of America 110, 8744-8749.
    DOI: 10.1073/pnas.1221294110
  • Herde, M., Koo, A.J.K., Howe, G.A. (2013): Elicitation of jasmonate-mediated defense responses by mechanical wounding and insect herbivoryMethods in Molecular Biology 1011, 51-61.
    DOI: 10.1007/978-1-62703-414-2_5
  • Nakata, M., Mitsuda, N.,Herde, M., Koo, A.J.K., Moreno, J.E., Suzuki, K., Howe, G.A., Ohme-Takagi, M. (2013): A bHLH-type transcription factor, ABA-INDUCIBLE BHLH-TYPE TRANSCRIPTION FACTOR/JA-ASSOCIATED MYC2-LIKE1, acts as a repressor to negatively regulate jasmonate signaling in ArabidopsisThe Plant Cell 25, 1641-1656.
    DOI: 10.1105/tpc.113.111112
  • Schulz, P., Herde, M., Romeis, T. (2013): Calcium-Dependent Protein Kinases: Hubs in plant stress signaling and developmentPlant Physiology 163, 523-530.
    DOI: 10.1104/pp.113.222539
  • Werner, A.K., Medina-Escobar, N., Zulawski, M., Sparkes, I.A., Cao, F.Q., Witte, C.P. (2013): The ureide degrading reactions of purine ring catabolism employ one aminohydrolase and three amidohydrolases in Arabidopsis, soybean and ricePlant Physiology 163, 672-681.
    DOI: 10.1104/pp.113.224261
  • Claus-Peter Witte (2012): Die Remobilisierung von Stickstoff aus Nukleotiden und Harnstoff in Pflanzen. Habilitation in Botanik am Fachbereich für Biologie, Chemie und Pharmazie der Freien Universität Berlin
  • Führs, H., Specht, A., Erban, A., Kopka, J., Horst, W.J. (2012): Functional associations between the metabolome and manganese tolerance in Vigna unguiculataJournal of Experimental Botany Vol. 63, No. 1, pp 329-340
  • Klug, B., Specht, A., Horst, W.J. (2011): Aluminium localisation in root tips of the aluminium-accumulating plant species buckwheat (Fagopyrum esculentum Moench)Journal of Experimental Botany Vol. 62, No. 15, pp. 5453-5462
  • WANG, Y., SPECHT, A., HORST, W.J. (2011): Stable isotope labelling and zinc distribution in grains studied by laser ablation ICP-MS in an ear culture system reveals zinc transport barriers during grain filling in wheat.New Phytologist 189, 428-437.
  • Werner, A.K., Witte, C.P. (2011): The biochemistry of nitrogen mobilization: purine ring catabolismTrends in Plant Science 16, 381-387.
    DOI: 10.1016/j.tplants.2011.03.012
  • Witte, C.P. (2011): Urea metabolism in plantsPlant Science 180, 431-438.
    DOI: 10.1016/j.plantsci.2010.11.010
  • Cao, F.Q., Werner, A.K., Dahncke, K., Romeis, T., Liu, L.H., Witte, C.P. (2010): Identification and characterization of proteins involved in rice urea and arginine catabolismPlant Physiology 154, 98-108.
    DOI: 10.1104/pp.110.160929
  • Lee, S., Badieyan, S., Bevan, D., Herde, M., Gatz, C., Tholl, D. (2010): Herbivore-induced and floral homoterpene volatiles are biosynthesized by a single CytP450 enzyme (CYP82G1) in Arabidopsis Proceedings of the National Academy of Sciences of the United States of America 107, 21205-21210.
    DOI: 10.1073/pnas.1009975107
  • Werner, A.K., Romeis, T., Witte, C.P. (2010): Ureide catabolism in Arabidopsis thaliana and Escherichia coli Nature Chemical Biology 6, 19-21.
    DOI: 10.1038/nchembio.265
  • Witte, C.P, Dubiella, U., Seal, A., Zappel, N., Demoulière, R., Romeis, T. (2010): Tobacco calcium-dependent protein kinases are differentially phosphorylated in vivo as part of a kinase cascade that regulates stress responseJournal of Biological Chemistry 285, 9740-9748.
    DOI: 10.1074/jbc.M109.052126
  • FÜHRS, H., GÖTZE, S., SPECHT, A., ERBAN, A., GALLIEN, S., HEINTZ, D., VAN DORSSELAER, A., KOPKA, J., BRAUN, H.-P., HORST, W.J. (2009): Characterization of leaf apoplastic peroxidases and metabolites in Vigna unguiculata in response to toxic manganese supply and silicon.J. Exp. Bot. 60, 1663-1678.
  • Herde, M., Gärtner, K., Köllner, T.G., Fode, B., Boland, W., Gershenzon, J., Gatz, C., Tholl, D. (2008): Identification and regulation of TPS04/GES, an Arabidopsis geranyllinalool synthase catalyzing the first step in the formation of the insect-induced volatile C16-homoterpene TMTTThe Plant Cell 20, 1152-1168.
    DOI: 10.1105/tpc.106.049478
  • Werner, A.K., Sparkes, I.A., Romeis, T., Witte, C.P. (2008): Identification, biochemical characterization, and subcellular localization of allantoate amidohydrolases from Arabidopsis and soybeanPlant Physiology 146, 418-430.
    DOI: 10.1104/pp.107.110809
  • Noël, L.D., Cagna, G., Stuttmann, J., Wirthmüller, L., Betsuyaku, S., Witte, C.P., Colby, T. and Parker, J.E. (2007): Interaction between SGT1 and cytosolic/nuclear HSC70 chaperones regulates Arabidopsis immune responsesPlant Cell 19, 4061-4076.
  • Böhmer, M., Kurth, J., Witte, C.P., Romeis, T. (2005): Function of plant Calcium-Dependent Protein Kinases in the activation of abiotic and pathogen-related stress responses and its potential application in the generation of stress-resistant plantsFloriculture, Ornamental and Plant Biotechnology: Advances and Topical Issues (1st Edition), J.A. Teixeira da Silva, ed (New Dehli):Regency Publications.
  • Witte, C.P., Rosso, M.G., Romeis, T. (2005): Identification of three urease accessory proteins that are required for urease activation in Arabidopsis thalianaPlant Physiology 139, 1155-1162.
  • Witte, C.P., Tiller, S., Isidore, E., Davies, H.V., Taylor, M.A. (2005): Analysis of two alleles of the urease gene from potato: polymorphisms, expression and extensive alternative splicing of the corresponding mRNA Journal of Experimental Botany 56, 91-99.
  • Iannetta, P.P., Medina Escobar, N., Ross, H.A., Souleyre, E.J.F., Hancock, R.D., Witte, C.P., Davies, H.V. (2004): Identification, cloning and expression analysis of strawberry (Fragaria ananassa) mitochondrial citrate synthase and mitochondrial malate dehydrogenasePhysiologia Plantarum 121, 15-26.
  • Witte, C.P., Noel, L.D., Gielbert, J., Parker, J.E., Romeis, T. (2004): Rapid one-step protein purification from plant material using the eight-amino acid StrepII epitopePlant Molecular Biology 55, 135-147.
  • Ataya, F.S., Witte, C.P., Galvan, A., Igeno, M.I., Fernandez, E. (2003): Mcp1 encodes the molybdenum cofactor carrier protein in Chlamydomonas reinhardtii and participates in protection, binding, and storage functions of the cofactorJournal of Biological Chemistry 278, 10885-10890.
  • Glinski, M., Romeis, T., Witte, C.P., Wienkoop, S., Weckwerth, W. (2003): Stable isotope labeling of phosphopeptides for multiparallel kinase target analysis and identification of phosphorylation sitesRapid Communications in Mass Spectrometry 17, 1579-1584.
  • Bacanamwo, M., Freyermuth, S.K., Palacios, J.M., Witte, C.P., Polacco, J.C. (2002): Nitrification, denitrification and the N cycleFinan, T.M., O´Brian, M.R., Layzell, D.B., Vessey, J.K., Newton, W., eds., Nitrogen Fixation: Global Perspectives. CABI Publishing, Hamilton, Ontario, UK, pp 314-318.
  • Bacanamwo, M., Witte, C.P., Lubbers, M.W., Polacco, J.C. (2002): Activation of the urease of Schizosaccharomyces pombe by the UreF accessory protein from soybeanMolecular Genetics and Genomics 268, 525-534.
  • Witte, C.P., Tiller, S.A., Taylor, M.A., Davies, H.V. (2002): Leaf urea metabolism in potato. Urease activity profile and patterns of recovery and distribution of N-15 after foliar urea application in wild-type and urease-antisense transgenics Plant Physiology 128, 1129-1136.
  • Witte, C.-P., Isidore, E., Tiller, S.A., Davies, H.V., Taylor, M.A. (2001): Functional characterisation of urease accessory protein G (ureG) from potato Plant Molecular Biology 45, 169-179.
  • Witte, C.-P., Medina-Escobar, N. (2001): In-gel detection of urease with nitroblue tetrazolium and quantification of the enzyme from different crop plants using the indophenol reaction Analytical Biochemistry 290, 102-107.
  • Witte, C.-P., Tiller, S.A., Taylor, M.A., Davies, H.V. (2001): Addition of nickel to Murashige & Skoog medium in plant tissue culture activates urease and may reduce metabolic stressPlant Cell, Tissue and Organ Culture 68, 103-104.
  • Witte, C.P. (2001): Modifying Nitrogen Use Efficiency: Molecular Manipulation of Urea Metabolism in Leaves of Solanum tuberosumPromotion an der Universität Dundee in der Abteilung für Biochemie des Scottish Crop Research Institute, Dundee, Großbritannien.
  • Witte, C.P., Hien Le, Q., Bureau, T., Kumar, A. (2001): Terminal-repeat retrotransposons in miniature (TRIM) are involved in restructuring plant genomesProceedings of the National Academy of Sciences of the United States of America, 13778-13783.
  • Witte, C.-P., Blasco, R., Castillo, F. (1998): Microbial photodegradation of aminoarenes. Metabolism of 2-amino-4-nitrophenol by Rhodobacter capsulatus Applied Biochemistry and Biotechnology 69, 192-202.
  • Witte, C.-P., Igeño, M.I., Mendel, R., Schwarz, G., Fernández, E. (1998): The Chalmydomonas reinhardtii MoCo Carrier Protein is multimeric and stablilizes molybdopterin cofactor in a molybdate charged form FEBS Letters 431, 205-209.